

| Dosage | Package | Price per Dose | Price | |
|---|---|---|---|---|
| 250mg | 360 pills | C$0.99 | C$418.29 C$355.55 Best Price | |
| 250mg | 180 pills | C$1.18 | C$250.06 C$212.55 | |
| 250mg | 90 pills | C$1.78 | C$188.67 C$160.37 | |
| 250mg | 60 pills | C$2.07 | C$145.48 C$123.66 | |
| 250mg | 30 pills | C$2.76 | C$97.74 C$83.08 | |
| 500mg | 360 pills | C$1.08 | C$459.21 C$390.33 Popular | |
| 500mg | 120 pills | C$1.62 | C$229.60 C$195.16 | |
| 500mg | 90 pills | C$1.97 | C$209.13 C$177.76 | |
| 500mg | 60 pills | C$2.36 | C$165.94 C$141.05 | |
| 500mg | 30 pills | C$2.90 | C$102.28 C$86.94 |
Disclaimer: This information is for general understanding and is not a substitute for medical advice. Consult a healthcare professional for advice about your specific situation.
Principen is the brand name for ampicillin, an antibiotic in the penicillin family. It is used to treat certain bacterial infections as determined by a clinician. It works by interfering with the bacteria’s ability to form a sturdy cell wall, helping the body’s immune system clear the infection.
In Canada, access to Principen may require a prescription depending on local rules and the formulation you receive. The exact product and instructions will come from your pharmacist or prescriber. Always follow the label and your healthcare professional’s directions.
Principen is not effective against viral infections such as colds, flu, or most viral sinus infections. It should only be used for bacterial infections where a clinician has determined that an antibiotic is appropriate. Do not use antibiotics to treat symptoms without medical advice.
The medicine may be given as an oral capsule or liquid for home use, or by injection in a clinical setting. The form prescribed depends on the infection being treated and the patient’s needs. Your clinician will specify the form and the dosage you should take.
Finish the entire course of therapy unless your clinician tells you to stop early. Stopping too soon can allow bacteria to continue to grow and may lead to a return of infection or antibiotic resistance. If symptoms persist or worsen, contact your healthcare provider promptly.
Principen is used to treat a range of bacterial infections when the bacteria causing the illness are susceptible to ampicillin. Your clinician will decide if this antibiotic is appropriate for your infection. If you have a penicillin allergy, tell your clinician before receiving this medicine.
Typical uses include infections of the respiratory tract, ears, throat, and sinus areas, as well as skin and soft tissue infections. It can also be used for some urinary tract infections and certain abdominal infections when caused by susceptible bacteria. In some cases, it may be used to prevent infection in specific surgical situations or to treat other conditions as directed by a clinician.
Principen does not treat viral infections or illnesses caused by viruses. It is only effective against bacteria that are sensitive to ampicillin. The exact indication for your case will be determined by your doctor based on the infection and local guidelines.
Common indications for which ampicillin-containing medicines have historically been used include a variety of bacterial infections where a clinician judges this drug appropriate. Always rely on your clinician’s assessment. If you have questions about why this medicine was chosen for you, ask your pharmacist or doctor for clarification.
Possible uses are determined by the specific bacterial cause and the patient’s medical history. The key is that Principen should be used only under medical supervision and with a clear diagnosis that supports its use. Do not self-diagnose or self-treat with antibiotics.
Ampicillin, the active ingredient in Principen, is a bactericidal antibiotic. It targets the building of the bacterial cell wall, a structure essential for bacterial survival. By weakening the wall, bacteria are more likely to be killed by normal immune mechanisms.
Because Principen acts on a fundamental component of bacterial growth, its effectiveness depends on the specific bacteria involved and its susceptibility to ampicillin. Some bacteria have or can develop resistance, so the choice of antibiotic depends on clinical judgment and sometimes lab testing.
Principen does not work against viruses or non-bacterial infections. Its use should be limited to conditions where a clinician has determined that the infection is due to bacteria that respond to ampicillin. If your infection does not improve or worsens, contact your clinician for reassessment.
Understanding antibiotic choice helps in appreciating why a doctor may select Principen for a given illness. If you have questions about how this medicine affects your specific infection, discuss them with your healthcare provider.
Take this medicine exactly as prescribed by your clinician. Do not change the dose or duration without professional guidance. If you are using a suspension, shake the bottle well before measuring each dose. Use the measuring device provided by your pharmacist to ensure the correct amount.
The form you receive (capsule, tablet, or liquid) and the timing will be tailored to your infection and needs. The clinician may prescribe it to be taken with or without food depending on the formulation and tolerability. Always follow the directions on the label and solicit clarification if anything is unclear.
Complete the full course of therapy even if you start feeling better. Stopping early may allow the infection to return and can contribute to antibiotic resistance. Do not share your medication with others, and do not use someone else’s leftover antibiotics.
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to make up for a missed one. If you are unsure what to do after missing a dose, contact your pharmacist or clinician for advice.
Store Principen as directed on the label, away from light and moisture. Keep all medicines out of reach of children. If you have kidney disease or other chronic conditions, tell your clinician, as dosage adjustments may be necessary. If you develop severe side effects or signs of an allergic reaction, seek urgent medical help immediately.
Do not take Principen if you have a known allergy to ampicillin or other penicillins, or to any ingredient in the product. Severe allergic reactions, though uncommon, require immediate medical attention. Tell your clinician about any history of allergies to medicines or severe reactions to antibiotics.
People with certain health conditions, including significant kidney disease, may require dosage adjustments or alternative therapies. Your clinician will determine if Principen is appropriate for you based on your medical history and current health status.
Ampicillin can interact with some medical conditions, such as mononucleosis, which can increase the risk of rash if treated with ampicillin. If you have mono or a history of this condition, discuss it with your clinician before starting Principen.
Pregnant or breastfeeding individuals should discuss the risks and benefits with a healthcare professional before using this medicine. Your clinician will consider potential effects on the fetus or infant and determine if this antibiotic is suitable for you during pregnancy or while nursing.
Allergic reactions to penicillins can be severe. If you notice hives, swelling of the face or throat, trouble breathing, or a severe rash, seek urgent medical help. Stop taking Principen if you experience signs of a serious allergic reaction and contact your clinician immediately.
Common gastrointestinal symptoms such as nausea, vomiting, or stomach upset may occur. Seek medical advice if you develop persistent diarrhea, especially if it is severe or contains blood or mucus, as this could indicate a more serious condition.
Ampicillin use has been associated with antibiotic-associated diarrhea and, in rare cases, more serious intestinal conditions. If you have any persistent or worsening stomach symptoms, discuss them with your clinician. Tell your clinician if you have a history of intestinal disease.
Principen can affect laboratory tests and the results of certain medical tests. Inform all health professionals that you are taking this medicine prior to any test. If you are scheduled for vaccines or labs, discuss potential timing with your clinician.
Prolonged use can lead to overgrowth of non-susceptible organisms, including fungi. If you notice new or worsening symptoms such as itching, unusual vaginal discharge, or mouth sores, talk to your clinician about management options.
If you develop a severe rash or adverse effects, discontinue use and seek medical help promptly. Always use this medicine under medical supervision and report any new symptoms to your healthcare team.
Common side effects include mild nausea, vomiting, diarrhea, or upset stomach. Some people may experience mouth or tongue changes, skin rash, or yeast infections such as vaginal itching or thrush.
Serious side effects requiring medical attention include signs of an allergic reaction (rash, itching, swelling, severe dizziness, trouble breathing), severe or persistent diarrhea, or jaundice (yellowing of skin or eyes). If any of these occur, contact a clinician or seek urgent care.
Long-term or frequent use may increase the risk of yeast infections or other infections caused by changes in normal bacteria. If you notice unusual symptoms, inform your healthcare provider.
Not all side effects are listed here. If you experience anything unusual after starting Principen, speak with your pharmacist or clinician for guidance. Do not ignore new or worsening symptoms.
Tell your clinician about all medicines you take, including over‑the‑counter drugs, vitamins, and herbal supplements. Some medicines can interact with ampicillin and change how well it works or increase side effects.
Potential interactions may include medicines that affect kidney function or that rely on similar metabolic pathways. Examples often discussed include agents such as probenecid and certain anticoagulants, but your clinician will review all possibilities based on your health history.
Oral contraceptives may be affected by antibiotics in some circumstances; use additional contraceptive methods if advised by your clinician. If you are taking other antibiotics or medicines that affect the gut, discuss this with your pharmacist, as the combination can influence effectiveness or side effects.
If you are scheduled for lab tests, inform the laboratory staff that you are taking ampicillin. Some tests can be affected by antibiotics, and this awareness helps ensure accurate results.
During pregnancy, the decision to use Principen should be made by a clinician based on the balance of benefits and risks. Ampicillin has been used in pregnancy when medically required, but every case is different. Do not start or stop antibiotics during pregnancy without professional advice.
Ampicillin can pass into breast milk in small amounts. If you are breastfeeding, discuss with your clinician whether to continue breastfeeding during treatment and how to monitor the infant for any signs of reaction or adverse effects.
If you become pregnant while taking Principen, contact your healthcare provider promptly to review your treatment plan. Do not alter your medication without guidance from a clinician.
Always discuss pregnancy, planning a pregnancy, or breastfeeding with a healthcare professional before starting or continuing this antibiotic. They can help determine the safest option for you and your baby.
People often notice improvement in symptoms within a day or two, but this can vary. Some infections may take longer to improve. If there is no improvement after 2–3 days, contact your clinician for guidance.
Principen may require a prescription depending on local rules and the formulation. In Canada, access can vary by province and product. Check with your pharmacist or clinician for local requirements.
If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to make up for a missed one. If you are unsure what to do, contact your pharmacist or clinician for advice.
There is no known dangerous interaction between ampicillin and moderate alcohol, but alcohol can worsen some side effects such as stomach upset. If you have concerns, discuss them with your clinician.
Always tell your clinician about all medicines you take. Some combinations can increase side effects or affect how well either medicine works. Your clinician or pharmacist can review potential interactions for you.
Contact your clinician if you develop signs of a severe allergic reaction, persistent or worsening diarrhea, fever lasting more than a couple of days, or any severe or unusual symptoms. Seek urgent medical help if you have trouble breathing or swelling of the face or throat.
It can affect some laboratory tests. Inform your healthcare provider about all medicines you are taking before undergoing tests or starting a new vaccine schedule. Vaccines themselves are generally not contraindicated, but timing may be adjusted in some cases.
Ampicillin-based medicines can be used in children when prescribed by a clinician. Dosing for children depends on age, weight, and the infection being treated. A clinician will determine the appropriate plan for a child.
Even if you feel better, continue taking Principen for the full prescribed course. Stopping early can allow the infection to return and can contribute to antibiotic resistance.
If you experience a severe allergic reaction, stop taking Principen and seek urgent medical help. Contact your clinician as soon as possible to discuss alternative treatments.
Official product labeling for ampicillin-based medicines and patient information resources from Health Canada and provincial health services.
Canadian pharmacology and pharmacy practice references and patient information materials used to guide antibiotic use in Canada.
General guidelines from national infection control and antimicrobial stewardship resources, adapted for patient education in a Canadian context.
14–21 days. Free from C$276.06 .
5–9 days. C$41.41
−10% when paying with cryptocurrency.
−10% on all repeat orders.
All orders are packed in neutral, unbranded boxes with no product name on the outside.
