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|---|---|---|---|
| 360 pills | C$1.30 | C$666.93 C$466.85 Free shipping | |
| 270 pills | C$1.32 | C$509.18 C$356.43 Free shipping | |
| 180 pills | C$1.38 | C$354.21 C$247.95 | |
| 120 pills | C$1.49 | C$254.58 C$178.21 | |
| 90 pills | C$1.57 | C$202.00 C$141.40 | |
| 60 pills | C$1.67 | C$143.88 C$100.72 | |
| 30 pills | C$1.84 | C$80.23 C$56.16 | |
| 10 pills | C$2.05 | C$30.41 C$21.29 | |
| 360 pills | C$1.82 | C$935.37 C$654.76 Free shipping | |
| 270 pills | C$1.88 | C$725.05 C$507.53 Free shipping | |
| 180 pills | C$1.94 | C$498.12 C$348.68 Free shipping | |
| 120 pills | C$2.03 | C$348.67 C$244.07 | |
| 90 pills | C$2.17 | C$279.49 C$195.64 | |
| 60 pills | C$2.32 | C$199.23 C$139.46 | |
| 30 pills | C$2.56 | C$110.67 C$77.47 |
Celecoxib was approved by the FDA in 1998 and became one of the most used COX-2 inhibitors for pain relief. It belongs to the NSAID family, but it targets a specific enzyme that drives inflammation. By narrowing its action, Celecoxib can ease joint swelling and stiffness while sparing the stomach from as much irritation as older pain medicines.
You take it by mouth as a capsule. Your clinician will decide when and how long you should take it, based on your pain, medical history, and other medicines you take. It is used for chronic conditions like arthritis, and for short-term discomfort such as after dental work or minor injuries. Always follow the exact directions you are given.
Primary therapeutic uses include osteoarthritis, which brings joint pain and reduced movement, and rheumatoid arthritis, an autoimmune inflammation of the joints. Celecoxib helps lower the pain signals and swelling that come with these conditions, so daily tasks feel easier. It can also help with ankylosing spondylitis, a spinal inflammatory disease that affects posture and mobility.
Secondary indications cover short-term pain after surgery or dental procedures, menstrual cramps, and other inflammatory problems when a clinician considers COX-2 inhibition. Some people use it for flareups of back strain or other injuries, but this should be done under medical supervision. It can be selected when nonselective NSAIDs cause stomach upset or reactions.
Mechanism in plain terms: Celecoxib blocks the COX-2 enzyme. That enzyme helps make prostaglandins, the chemicals that signal pain and swelling. By reducing those signals, you notice less soreness and stiffness. The effect grows with regular dosing, and it may take several days to reach the full benefit.
Because Celecoxib is selective for COX-2, it tends to be kinder to the stomach than older NSAIDs that hit both COX-1 and COX-2. It can still irritate the gut in some people. Long-term use may raise blood pressure, affect kidney function, and increase the chance of heart-related events, which is why your doctor checks you regularly.
Common side effects include stomach upset, heartburn, indigestion, diarrhea, and headaches. Some people may notice dizziness or swelling in the ankles or feet. If you experience severe stomach pain, dark stools, persistent vomiting, or unusual fatigue, contact your clinician.
Safety notes: Tell your doctor about heart disease, high blood pressure, kidney or liver problems, or a history of ulcers. Celecoxib may interact with blood thinners, other NSAIDs, or certain antidepressants, so share all medicines you take. Do not take it during pregnancy unless your clinician says it is safe.
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